GeneID = 347051 is in our transporter list.
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  • Gene general annotation
  • Data comes from NCBI-Gene
    Entrez GeneID 347051
    Gene Symbol SLC10A5
    Aliases P5
    Description solute carrier family 10 (sodium/bile acid cotransporter family), member 5
    Organism Homo sapiens
    Location 8q21.13
    Genomic position NC_000008.10 82605890-82607206 minus strand (Reference GRCh37.p5 Primary Assembly) U E
    UniProt Accession Q5PT55
    Mammalian Homolog
    (GeneID)
    mouse : 241877
    rat : 310230
  • KOBAS Annotation (Pathway/Disease Annotation)
  • PharmacoGenetics Related Genes/Drugs/Diseases
  • TaxicoGenetics Related Chemicals/Diseases/Pathways
  • Known Drugs in DrugBank
  • Transporter Substrate Information
  • Data comes from (unpublished integrated data)
    KEGG Compound ID:
    C01330C01558
  • Genomic Variation --- SNP
  • Data is integrated from dbSNP and HapMap, with functionally annotated by ANNOVAR
    Note: heterozygosity is not actually estimated from 1KG data, but is put in the same line for more compact representation.
    dbSNP rsIDchrpositionpop.alleleallele countfrequencyHapMap pop. diff.genotypegenotype count (frequency) functional annotation
    rs4546615 8 82605748 1KG A (minor)1010 in 2178 = 0.46373 heterozygosity = 0.49737, with SE = 0.03618 downstream: SLC10A5
    rs7012758 8 82606348 ASW A / G 108 / 4 FET lg p = -4.29

    max diff AF = 0.068
    A/A / A/G / G/G 52 / 4 / 0 exonic: SLC10A5

    nonsynonymous SNV: SLC10A5, NM_001010893, exon1, c.T860C, p.I287T

    SIFT score = 0.33

    PolyPhen2 score = 0.00
    CEU 126 / 0 63 / 0 / 0
    CHB 88 / 0 44 / 0 / 0
    JPT 86 / 0 43 / 0 / 0
    LWK 205 / 13 96 / 13 / 0
    MEX 113 / 1 56 / 1 / 0
    MKK 307 / 5 151 / 5 / 0
    YRI 274 / 20 128 / 18 / 1
    1KG G (minor)37 in 2178 = 0.01699 heterozygosity = 0.03340, with SE = 0.12484
    rs6995098 8 82606416 CEU T / C 127 / 1 FET lg p = -3.48

    max diff AF = 0.119
    T/T / C/T / C/C 63 / 1 / 0 exonic: SLC10A5

    synonymous SNV: SLC10A5, NM_001010893, exon1, c.A792G, p.S264S
    CHB 79 / 11 34 / 11 / 0
    JPT 83 / 7 38 / 7 / 0
    YRI 110 / 16 49 / 12 / 2
    1KG C (minor)164 in 2178 = 0.07530 heterozygosity = 0.13926, with SE = 0.22413
    rs2955006 8 82606782 CEU A / G 57 / 71 FET lg p = -15.31

    max diff AF = 0.485
    A/A / A/G / G/G 14 / 29 / 21 exonic: SLC10A5

    synonymous SNV: SLC10A5, NM_001010893, exon1, c.T426C, p.N142N
    CHB 80 / 6 37 / 6 / 0
    JPT 71 / 15 30 / 11 / 2
    YRI 67 / 49 22 / 23 / 13
    1KG G (minor)886 in 2178 = 0.40680 heterozygosity = 0.48263, with SE = 0.09157
    rs2955004 8 82607752 CEU G / C 58 / 72 FET lg p = -19.35

    max diff AF = 0.487
    G/G / C/G / C/C 14 / 30 / 21 upstream: SLC10A5
    CHB 84 / 6 39 / 6 / 0
    JPT 73 / 13 31 / 11 / 1
    YRI 61 / 65 14 / 33 / 16
    1KG C (minor)981 in 2178 = 0.45041 heterozygosity = 0.49508, with SE = 0.04934
    Limited to 5 records in this page. Click here to view more.
  • Genomic Variation --- CNV
  • Haplotype Information
  • Data links to UCSC Genome Browser
    ContentHyperlinkDemo example
    HapMap LD Structure (hg18)UCSC
    1000 Genomes Phase I Haplotype Clustering (hg19)UCSC
    Gene Haplotype Allele (hg19)UCSC
  • ENCODE TFBS (Transcription Factor Binding Sites) Information
  • Epigenetic Information
  • Gene Ontology (GO)
  • Protein Sequence & Features
  • Protein Domain Information
  • Protein-Protein Interaction
  • UniGene EST Expression Data
  • Allen Brain Atlas - Mouse Brain Expression Data
  • RNA-seq Expression Data
  • External Links
  • EntrezGeneID 347051
    Gene Symbol and
    Genome Browser
    SLC10A5
    UCSC Ensembl
    mRNA NM_001010893
    protein NP_001010893
    Ensembl ENST00000379063; ENSP00000368353; ENSG00000205184
    HPRD 18053
    UniProt Accession Q5PT55
    GeneCards GC08M082605
    UniGene Hs.683849
    HomoloGene 78106
    EMBL AY825924; AK095808; BC136625; BC136631
    IPI IPI00401216
    PRIDE Q5PT55
    STRING Q5PT55
    PharmGKB PA134933839