GeneID = 29986 is in our transporter list.
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  • Gene general annotation
  • Data comes from NCBI-Gene
    Entrez GeneID 29986
    Gene Symbol SLC39A2
    Aliases 6A1,ETI-1,MGC119190,ZIP-2,ZIP2
    Description solute carrier family 39 (zinc transporter), member 2
    Organism Homo sapiens
    Location 14q11.2
    Genomic position NC_000014.8 21467413-21470033 plus strand (Reference GRCh37.p5 Primary Assembly) U E
    UniProt Accession G3V5X2; Q9NP94
    Mammalian Homolog
    (GeneID)
    mouse : 214922
    rat : 305846
  • KOBAS Annotation (Pathway/Disease Annotation)
  • Data comes from KOBAS
    Pathway IDPathway NamePathway Database
    REACT:15518 Transmembrane transport of small molecules Reactome
  • PharmacoGenetics Related Genes/Drugs/Diseases
  • TaxicoGenetics Related Chemicals/Diseases/Pathways
  • Known Drugs in DrugBank
  • Transporter Substrate Information
  • Data comes from (unpublished integrated data)
    KEGG Compound ID:
    C00038
  • Genomic Variation --- SNP
  • Data is integrated from dbSNP and HapMap, with functionally annotated by ANNOVAR
    Note: heterozygosity is not actually estimated from 1KG data, but is put in the same line for more compact representation.
    dbSNP rsIDchrpositionpop.alleleallele countfrequencyHapMap pop. diff.genotypegenotype count (frequency) functional annotation
    rs945353 14 21466579 ASW T / C 110 / 4 FET lg p = -56.32

    max diff AF = 0.306
    T/T / C/T / C/C 53 / 4 / 0 upstream: SLC39A2
    CEU 224 / 2 111 / 2 / 0
    CHB 192 / 82 64 / 64 / 9
    CHD 148 / 68 50 / 48 / 10
    GIH 189 / 13 88 / 13 / 0
    JPT 155 / 67 55 / 45 / 11
    LWK 208 / 12 98 / 12 / 0
    MEX 115 / 1 57 / 1 / 0
    MKK 298 / 14 142 / 14 / 0
    YRI 274 / 18 129 / 16 / 1
    1KG C (minor)239 in 2178 = 0.10973 heterozygosity = 0.19539, with SE = 0.24396
    rs945352 14 21466781 ASW T / C 51 / 63 FET lg p = -42.66

    max diff AF = 0.448
    T/T / C/T / C/C 12 / 27 / 18 upstream: SLC39A2
    CEU 120 / 106 35 / 50 / 28
    CHB 172 / 102 55 / 62 / 20
    CHD 151 / 67 53 / 45 / 11
    GIH 127 / 75 35 / 57 / 9
    JPT 165 / 61 60 / 45 / 8
    LWK 62 / 158 7 / 48 / 55
    MEX 80 / 36 26 / 28 / 4
    MKK 129 / 181 23 / 83 / 49
    TSI 136 / 68 45 / 46 / 11
    YRI 98 / 196 16 / 66 / 65
    1KG C (minor)928 in 2178 = 0.42608 heterozygosity = 0.48907, with SE = 0.07311
    rs945350 14 21466829 1KG T (minor)2 in 2178 = 0.00092 heterozygosity = 0.00183, with SE = 0.03023 upstream: SLC39A2
    rs2234629 14 21467048 CEU C / G 130 / 0 FET lg p = -6.10

    max diff AF = 0.098
    C/C / C/G / G/G 65 / 0 / 0 upstream: SLC39A2
    CHB 90 / 0 45 / 0 / 0
    JPT 90 / 0 45 / 0 / 0
    YRI 110 / 12 49 / 12 / 0
    1KG G (minor)43 in 2178 = 0.01974 heterozygosity = 0.03871, with SE = 0.13362
    rs2149666 14 21468156 ASW G / T 62 / 52 FET lg p = -27.09

    max diff AF = 0.367
    G/G / G/T / T/T 17 / 28 / 12 intronic: SLC39A2
    CEU 121 / 105 35 / 51 / 27
    CHB 179 / 95 60 / 59 / 18
    CHD 156 / 62 56 / 44 / 9
    GIH 128 / 74 35 / 58 / 8
    JPT 169 / 57 63 / 43 / 7
    LWK 83 / 135 13 / 57 / 39
    MEX 80 / 36 26 / 28 / 4
    MKK 145 / 159 33 / 79 / 40
    TSI 136 / 68 45 / 46 / 11
    YRI 117 / 175 21 / 75 / 50
    1KG T (minor)872 in 2178 = 0.40037 heterozygosity = 0.48015, with SE = 0.09763
    Limited to 5 records in this page. Click here to view more.
  • Genomic Variation --- CNV
  • Data comes from DGV
    Variation IDPositionVar. TypeGainLossTotal GL InvPubMed
    Variation_3930 chr14:21216108-21471614 U E CopyNumber 14 17122850
  • Haplotype Information
  • Data links to UCSC Genome Browser
    ContentHyperlinkDemo example
    HapMap LD Structure (hg18)UCSC
    1000 Genomes Phase I Haplotype Clustering (hg19)UCSC
    Gene Haplotype Allele (hg19)UCSC
  • ENCODE TFBS (Transcription Factor Binding Sites) Information
  • Epigenetic Information
  • Gene Ontology (GO)
  • Protein Sequence & Features
  • Protein Domain Information
  • Protein-Protein Interaction
  • UniGene EST Expression Data
  • Allen Brain Atlas - Mouse Brain Expression Data
  • RNA-seq Expression Data
  • External Links
  • EntrezGeneID 29986
    Gene Symbol and
    Genome Browser
    SLC39A2
    UCSC Ensembl
    mRNA NM_001256588; NM_014579; NR_033419
    protein NP_001243517; NP_055394
    Ensembl ENST00000298681; ENSP00000298681; ENSG00000165794
    HPRD 15385
    UniProt Accession G3V5X2; Q9NP94
    GeneCards GC14P021467
    UniGene Hs.175783
    HomoloGene 40957
    EMBL D83039; AF186081; AK314974; AL161668; AL355922; BC096723; BC098254; BC110057; AY029483
    IPI IPI00005148
    PRIDE Q9NP94
    STRING Q9NP94
    TCDB 2.A.5.3.1
    OMIM 612166
    PharmGKB PA38202
    Reactome REACT_15518